Your search matched a total of 50 documents. Results 1 - 10.
Homo sapiens
Gene: ... Disease relevance of UGT2B7 Our results also have toxicogenetic significance, as UGT2B7... in UGT2B7 expression in carcinomas in situ. Two maltose binding protein fusion proteins, 2B7F1 and 2B7F2, incorporating the first 157 or 119 amino acids, respectively, of UGT2B7 were expressed in Escherichia coli...
Chemical compound: ... oxidized derivatives, 13- HODE and 13- OXO, by HLM and recombinant UGT2B7. No differences between the OA...
Chemical compound: ... in an uncompetitive manner and UGT2B7 catalyzed AZT glucuronidation competitively( K( i )= 1. 6 +/- 0. 06m..., was significantly associated with the postoperative complications at all seven hospitals. Propofol provides at least... than midazolam. Gene context of Disoprofol All of the CYPs evaluated were capable of hydroxylating...
Chemical compound: ... susceptibility to diclofenac- induced hepatotoxicity: contribution of UGT2B7, CYP2C8, and ABCC2 genotypes...
Chemical compound: ... , and cyclophosphamide. UGT2B7 is the major human UGT catalyzing epirubicin glucuronidation, and UGT2B7 is the candidate...
Rattus norvegicus
Gene: ... suppressed 50% in females and induced 120% over control in males. mRNA expression for all other forms of rat... relationships of LOC286989 All treatments except 3, 4- TBB induced NADPH- cytochrome P- 450 reductase and aminopyrine- N- demethylase activities while all treatments except 2, 4, 5- HBB induced ethoxyresorufin- O...
Homo sapiens
Gene: ... by UGT1A1. Caco- 2 cells treated with typical enzyme- inducing agents resulted in low UGT2B7 expression... indicate that UGT2B7 has one binding site and that UGT1A1 has two or more binding sites for xenobiotics...
Chemical compound: ... inhibition of gemcabene glucuronidation was similar in HLM( 60. 6 microM) compared with recombinant UGT2B7( 27. 4 microM ), consistent with a major role for UGT2B7 in gemcabene glucuronidation in HLM...
Homo sapiens
Gene: ... , reduce TNO to TAM. The effects of P450 isozymes on the kinetic parameters of UGT2B7- catalyzed glucuronidation of the morphine 3- hydroxyl group were examined by simultaneous expression of UGT2B7 and either...
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Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann
