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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Your search matched a total of 51 documents. Results 1 - 10.

Homo sapiens
Gene: ... , weak splicing of XBP1 mRNA was detected only in the C1264R mutant, all rat thyroids including wild...Disease relevance of XBP1 After exposure to hypoxia, apoptosis increased and clonogenic survival decreased in XBP1- deficient cells. Several recent studies have demonstrated that XBP- 1 mRNA expression... / Synonyms: XBP-1
Mus musculus
Gene: ... Disease relevance of Xbp1 When cells were infected with a recombinant adenovirus( AdV) encoding dominant- negative XBP1( AdV- XBP1dn ), UPR markers were reduced; however, hypoxia/ reoxygenation- induced apoptosis increased. Mouse hepatitis virus infection activates the Ire1/ XBP1 pathway of the unfolded... / Synonyms: XBP-1
XBP1  -  Xbp1p
Saccharomyces cerevisiae S288c
Gene: ... High impact information on XBP1 We propose that nuclear- localized IRE1alpha and cytoplasmic- localized ATF6 signaling pathways merge through regulation of XBP1 activity to induce downstream gene expression. Whereas ATF6 increases the amount of XBP1 mRNA, IRE1alpha removes an unconventional 26... / Synonyms: Transcriptional repressor XBP1
Caenorhabditis elegans
Gene: ... High impact information on xbp- 1 C. elegans requires ire- 1- mediated splicing of xbp- 1 mRNA for UPR gene transcription and survival upon ER stress. Biological context of xbp- 1 Knockdown by RNA interference of 9 known or predicted ER chaperones induced hsp- 4 upregulation via the ire- 1/ xbp- 1 signaling...
Drosophila melanogaster
Gene: ... Disease relevance of Xbp1 Here, we analyzed a branch of the UPR mediated by xbp1 in Drosophila to establish its role in neurodegenerative diseases.... / Synonyms: XBP-1; XBP1; Xbp-1
Homo sapiens
Gene: ... binding protein 1( hXBP- 1) was isolated as a down- regulated gene in advanced prostate cancers using c.... reported that the- 116C/ G polymorphism in the promoter region of the X- box binding protein 1( XBP- 1...) and X- box binding protein 1( XBP- 1) are required for plasma cell development. Expression of genes... / Synonyms: XBP1
Danio rerio
Gene: ... High impact information on xbp1 The zygotic expression of zebrafish trebf during embryogenesis is restricted to the embryonic shield and its derivatives. Northern hybridization reveals that trebf m... and mouse TREB5/ hXBP- 1/ HTF, respectively. Analytical, diagnostic and therapeutic context of xbp1 Whole... / Synonyms: xbp1a; xbp1b
Rattus norvegicus
Gene: ... Disease relevance of Xbp1 Hepatocarcinogenesis- related transcription factor( HTF) was originally... on Xbp1 Transformed cells carrying pmt in the vicinity of the HTF island have a propensity to revert... fibroblastic cell line FRL. Biological context of Xbp1 HTF induced cell adherence to the culture plate...
Pan troglodytes
Gene: Synonyms: XBP1P1
Caenorhabditis remanei


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