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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Chemical Compound Review: 

AC1L3QFM     6-(hydroxymethyl)-9-methoxy- phenazine-1...

Synonyms: AC1Q5UNJ, LL 14I352-beta, LL-14I352-beta, AR-1H0023, LS-102998, ...
 
 
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High impact information on Griseoluteic acid

  • In cell-free assays, both AGA and griseoluteic acid reduced cytochrome c in the presence of a redox recycler (ferredoxin-NADP(+) reductase), but AGA was six to seven times more readily reduced than griseoluteic acid in the absence of the reductase [1].
  • Isotopic labelling experiments with 15N-labelled ammonium sulfate demonstrated that wild-type Eh1087 incorporated 15N into griseoluteic acid more readily than the glnA mutant Eh7 [2].

References

  1. Investigations into the in vitro antimicrobial activity and mode of action of the phenazine antibiotic d-alanylgriseoluteic acid. Giddens, S.R., Bean, D.C. Int. J. Antimicrob. Agents (2007) [Pubmed]
  2. Role of glutamine synthetase in phenazine antibiotic production by Pantoea agglomerans Eh1087. Galbraith, M.D., Giddens, S.R., Mahanty, H.K., Clark, B. Can. J. Microbiol. (2004) [Pubmed]
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