Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

SureCN9150120 1-[(4S,5R)-4-hydroxy-5...

Synonyms: KST-1B9555, AR-1B0755, AC1L2NW4, AC1Q4P61, 99196-22-2

Seo, Y. et al., Seo, Y. et al., Chang, C.N. et al.

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Disease relevance of 5-Iodo-2-pyrimidinone-2'-deoxyribose

Differential radiosensitization in DNA mismatch repair-proficient and -deficient human colon cancer xenografts with 5-iodo-2-pyrimidinone-2'-deoxyribose [1].
Schedule-dependent drug effects of oral 5-iodo-2-pyrimidinone-2'-deoxyribose as an in vivo radiosensitizer in U251 human glioblastoma xenografts [2].

High impact information on 5-Iodo-2-pyrimidinone-2'-deoxyribose

Conversion of 5-iodo-2-pyrimidinone-2'-deoxyribose to 5-iodo-deoxyuridine by aldehyde oxidase. Implication in hepatotropic drug design [3].

References

Differential radiosensitization in DNA mismatch repair-proficient and -deficient human colon cancer xenografts with 5-iodo-2-pyrimidinone-2'-deoxyribose. Seo, Y., Yan, T., Schupp, J.E., Colussi, V., Taylor, K.L., Kinsella, T.J. Clin. Cancer Res. (2004) [Pubmed]
Schedule-dependent drug effects of oral 5-iodo-2-pyrimidinone-2'-deoxyribose as an in vivo radiosensitizer in U251 human glioblastoma xenografts. Seo, Y., Yan, T., Schupp, J.E., Radivoyevitch, T., Kinsella, T.J. Clin. Cancer Res. (2005) [Pubmed]
Conversion of 5-iodo-2-pyrimidinone-2'-deoxyribose to 5-iodo-deoxyuridine by aldehyde oxidase. Implication in hepatotropic drug design. Chang, C.N., Doong, S.L., Cheng, Y.C. Biochem. Pharmacol. (1992) [Pubmed]

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