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MeSH Review

Colonic Neoplasms

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Disease relevance of Colonic Neoplasms


Psychiatry related information on Colonic Neoplasms


High impact information on Colonic Neoplasms

  • Future directions being evaluated for adjuvant therapy of colon cancer include the use of oral fluorinated pyrimidines, which may replace current intravenous treatments, as well as the incorporation of new agents, such as oxaliplatin and CPT-11, into adjuvant chemotherapy programs [10].
  • Restoration of PITX1 in the colon cancer cells inhibited tumorigenicity in a wild-type RAS-dependent manner [11].
  • Because MLH1, MSH2 and MSH6 mutations underlie high-penetrance CRC susceptibility in hereditary nonpolyposis colon cancer (HNPCC), we hypothesized that attenuated alleles might also underlie susceptibility to sporadic CRC [12].
  • Forced activation of mTOR through upstream regulator Akt also increased ABI in colon cancer cells [13].
  • Here we report the positional cloning of the mouse gene Scc1 (Susceptibility to colon cancer 1) and the identification of Ptprj, encoding a receptor-type protein tyrosine phosphatase, as the underlying gene [14].

Chemical compound and disease context of Colonic Neoplasms


Biological context of Colonic Neoplasms


Anatomical context of Colonic Neoplasms


Gene context of Colonic Neoplasms


Analytical, diagnostic and therapeutic context of Colonic Neoplasms


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