Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AC1Q6JIP (7S,9R)-7-[(2S,4R,5S,6S)-4- amino-5-hydroxy...

Synonyms: AR-1G5789, AC1L2O9W, 66322-65-4, 3'-Epidaunorubicin, 4'-Epidaunorubicin, ...

Madduri, K. et al.

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Disease relevance of 4'-Epidaunorubicin

A fermentation method that bypasses the low-yielding semisynthesis of epirubicin (4'-epidoxorubicin) and 4'-epidaunorubicin, important cancer chemotherapy drugs, has been developed for Streptomyces peucetius [1].

References

Production of the antitumor drug epirubicin (4'-epidoxorubicin) and its precursor by a genetically engineered strain of Streptomyces peucetius. Madduri, K., Kennedy, J., Rivola, G., Inventi-Solari, A., Filippini, S., Zanuso, G., Colombo, A.L., Gewain, K.M., Occi, J.L., MacNeil, D.J., Hutchinson, C.R. Nat. Biotechnol. (1998) [Pubmed]

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