Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Chemical Compound Review:

Pregnane 17-ethyl-10,13-dimethyl- 2,3,4,5,6,7,8,9,11...

Synonyms: Allopregnane, HMDB05943, AC1L1ZTU, CTK8H7409, 641-85-0, ...

Rupprecht, R., Wiebe, J.P. et al.

Rupprecht, Wiebe, Muzia, Hu, Szwajcer, Hill, Seachrist,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on Pregnane

The 4-pregnene and 5alpha-pregnane progesterone metabolites formed in nontumorous and tumorous breast tissue have opposite effects on breast cell proliferation and adhesion [1].
On the other hand, also 3alpha-reduced neuroactive steroids may regulate gene expression via the progesterone receptor after intracellular oxidation into 5alpha-pregnane steroids [2].

References

The 4-pregnene and 5alpha-pregnane progesterone metabolites formed in nontumorous and tumorous breast tissue have opposite effects on breast cell proliferation and adhesion. Wiebe, J.P., Muzia, D., Hu, J., Szwajcer, D., Hill, S.A., Seachrist, J.L. Cancer Res. (2000) [Pubmed]
Neuroactive steroids: mechanisms of action and neuropsychopharmacological properties. Rupprecht, R. Psychoneuroendocrinology (2003) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

Editor

Share