Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

GS-Mal (2S)-4-[[(1S)-1- (carboxymethylcarbamoyl)-2...

Synonyms: AC1L2Q0B

Abbott, R.E. et al., Batt, E.R. et al.

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High impact information on Glutathione maleimide

Reaction of radioactive dextran-maleimide and glutathione-maleimide with either intact erythrocytes or ghosts yields sulfhydryl titers for the outer (exofacial) and inner (endofacial) surfaces, respectively, of 1.5 to 1.7 and 27 to 28 amol/cell [1].
The facilitated diffusion of D-glucose across human erythrocyte membranes requires an exofacial (outer surface) sulfhydryl group which can be alkylated by the impermeant reagents glutathione-maleimide and dextran-maleimide [2].

References

Impermeant maleimides. Oriented probes of erythrocyte membrane proteins. Abbott, R.E., Schachter, D. J. Biol. Chem. (1976) [Pubmed]
Impermeant maleimides. Identification of an exofacial component of the human erythrocyte hexose transport mechanism. Batt, E.R., Abbott, R.E., Schachter, D. J. Biol. Chem. (1976) [Pubmed]

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