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Chemical Compound Review

AC1L2SZH     (5S,6S)-6-(4-hydroxyphenyl)- 6-methyl-5-[9...

Synonyms: LS-183775, ZM 189154, ZM 189,154
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High impact information on ZM 189154

  • ZM 189,154 displays no intrinsic oestrogen-agonist activity on uterus, vagina, bone, LH secretion or growth rate in OVX rats [1].

Analytical, diagnostic and therapeutic context of ZM 189154


  1. Effects of a non-steroidal pure antioestrogen, ZM 189,154, on oestrogen target organs of the rat including bones. Dukes, M., Chester, R., Yarwood, L., Wakeling, A.E. J. Endocrinol. (1994) [Pubmed]
  2. Anti-estrogen prevents xenoestrogen-induced testicular pathology of eelpout (Zoarces viviparus). Rasmussen, T.H., Teh, S.J., Bjerregaard, P., Korsgaard, B. Aquat. Toxicol. (2005) [Pubmed]
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