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Chemical Compound Review

Cyanidin     2-(3,4- dihydroxyphenyl)chromene- 3,5,7-triol

Synonyms: Cyanidol, CHEMBL404515, CHEBI:27843, LMPK12010002, ZINC03775158, ...
 
 
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High impact information on Cyanidin chloride

  • As a result of a marked reduction of iAGH inhibitory activity by deacylating the anthocyanins, that is, Pg (or Cy or Pn) sophoroside-5-glucoside, acylation of anthocyanin with caffeic (Caf) or ferulic (Fer) acid was found to be important in the expression of iAGH (maltase) inhibition [1].
  • DP showed a major action compared to CY inducing a significant dose-dependent inhibitory effect on both protein and mRNA levels of ET-1 [2].
  • To correlate the vasoprotective effect of CY and DP with their antioxidant activity, we analysed also the antioxidant effect of anthocyanidins both in vitro and in HUVECs [2].
  • Aglycon anthocyanidin forms, such as CY and DP, may be present in vivo after the first deglycosylation step occurring in the jejunum and in the liver [2].

References

  1. alpha-Glucosidase inhibitory action of natural acylated anthocyanins. 2. alpha-Glucosidase inhibition by isolated acylated anthocyanins. Matsui, T., Ueda, T., Oki, T., Sugita, K., Terahara, N., Matsumoto, K. J. Agric. Food Chem. (2001) [Pubmed]
  2. Anthocyanidins decrease endothelin-1 production and increase endothelial nitric oxide synthase in human endothelial cells. Lazzè, M.C., Pizzala, R., Perucca, P., Cazzalini, O., Savio, M., Forti, L., Vannini, V., Bianchi, L. Molecular nutrition & food research. (2006) [Pubmed]
 
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