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Chemical Compound Review:

Isouvaretin 1-[4,6-dihydroxy-3-[(2...

Synonyms: NSC-295674, NSC295674, LMPK12120467, AC1L46SX, C09759, ...

Nakatani, N. et al., Hufford, C.D. et al.

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High impact information on Isouvaretin

Uvaretin and isouvaretin. Two novel cytotoxic c-benzylflavanones from uvaria chamae L [1].
Uvaretin, isouvaretin and diuvaretin, cytotoxic C-benzylated dihydrochalcones isolated from Uvaria acuminata, displayed growth inhibitory effects against human promyelocytic leukemia HL-60 cells [2].

References

Uvaretin and isouvaretin. Two novel cytotoxic c-benzylflavanones from uvaria chamae L. Hufford, C.D., Lasswell, W.L. J. Org. Chem. (1976) [Pubmed]
Induction of apoptosis in human promyelocytic leukemia cell line HL-60 by C-benzylated dihydrochalcones, uvaretin, isouvaretin and diuvaretin. Nakatani, N., Ichimaru, M., Moriyasu, M., Kato, A. Biol. Pharm. Bull. (2005) [Pubmed]

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