Chemical Compound Review:
Fenobam 3-(3-chlorophenyl)-1-(1- methyl-4-oxo-5H...
Synonyms:
Fenobamum, CHEMBL239800, SureCN111562, McN-3377, NPL-2009, ...
- Comparison of the binding pockets of two chemically unrelated allosteric antagonists of the mGlu5 receptor and identification of crucial residues involved in the inverse agonism of MPEP. Malherbe, P., Kratochwil, N., Mühlemann, A., Zenner, M.T., Fischer, C., Stahl, M., Gerber, P.R., Jaeschke, G., Porter, R.H. J. Neurochem. (2006)
- Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity. Porter, R.H., Jaeschke, G., Spooren, W., Ballard, T.M., Büttelmann, B., Kolczewski, S., Peters, J.U., Prinssen, E., Wichmann, J., Vieira, E., Mühlemann, A., Gatti, S., Mutel, V., Malherbe, P. J. Pharmacol. Exp. Ther. (2005)
- Phenyl ureas of creatinine as mGluR5 antagonists. A structure-activity relationship study of fenobam analogues. Wållberg, A., Nilsson, K., Osterlund, K., Peterson, A., Elg, S., Raboisson, P., Bauer, U., Hammerland, L.G., Mattsson, J.P. Bioorg. Med. Chem. Lett. (2006)