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Chemical Compound Review:

SureCN115659 2-hydroxy-4- (trifluoromethyl)benzoic acid

Synonyms: ACMC-1CP4M, AG-E-76060, ACN-S002285, ANW-27486, AC-13071, ...

Sánchez de Miguel, L. et al., Mis, R. et al.

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High impact information on 4-Trifluoromethylsalicylic acid

The main metabolite of triflusal, 2-hydroxy-4-trifluoromethylbenzoic acid (HTB), alone or in combination with acetylsalicylic acid, did not modify NO production by neutrophils [1].
In-vitro protein binding interaction between a metabolite of triflusal, 2-hydroxy-4-trifluoromethylbenzoic acid and other drugs [2].

References

Comparison of in vitro effects of triflusal and acetysalicylic acid on nitric oxide synthesis by human neutrophils. Sánchez de Miguel, L., Casado, S., Farré, J., García-Durán, M., Rico, L.A., Montón, M., Romero, J., Bellver, T., Sierra, M.P., Guerra, J.I., Mata, P., Esteban, A., López-Farré, A. Eur. J. Pharmacol. (1998) [Pubmed]
In-vitro protein binding interaction between a metabolite of triflusal, 2-hydroxy-4-trifluoromethylbenzoic acid and other drugs. Mis, R., Ramis, J., Conte, L., Forn, J. J. Pharm. Pharmacol. (1992) [Pubmed]

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