Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Isoputreanine 4-(3-aminopropylamino)butanoic acid

Synonyms: HMDB06009, AKOS011558576, AC1L5851, 66165-33-1, N-(3-aminopropyl)-4-aminobutyrate, ...

Muskiet, F.A. et al., Seiler, N. et al.

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High impact information on Isoputreanine

Circadian rhythmicity in the excretion of spermidine and (especially) isoputreanine was established and is discussed in the light of its implications for monitoring therapy of cancer [1].
The latter compound yields isoputreanine by hydrolysis [2].

References

Total polyamines and their non-alpha-amino acid metabolites simultaneously determined in urine by capillary gas chromatography, with nitrogen-phosphorus detector; and some clinical applications. Muskiet, F.A., van den Berg, G.A., Kingma, A.W., Fremouw-Ottevangers, D.C., Halie, M.R. Clin. Chem. (1984) [Pubmed]
N-(3-aminopropyl)pyrrolidin-2-one, a product of spermidine catabolism in vivo. Seiler, N., Knödgen, B., Haegele, K. Biochem. J. (1982) [Pubmed]

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