Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Chemical Compound Review:

Leucopyrokinin (2S)-N-[(1S,2R)-1-[[(1S)-1- [[(1S)-1-[[(2S...

Synonyms: AC1L41U7, 104052-00-8, Pglu-thr-ser-phe-thr-pro-arg-leu-NH2

Harshini, S. et al., Masler, E.P. et al., Nachman, R.J. et al., Plech, A. et al.

Plech, Rykaczewska-Czerwińska, Konopińska,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on Leucopyrokinin

Evaluation of analogs of the blocked insect myotropic neuropeptide leucopyrokinin (LPK) has demonstrated its relative insensitivity to amino acid substitution in the N-terminal in contrast to the C-terminal region [1].
In addition, the C-terminal pentapeptide sequences of Pseudaletia pheromonotropin (Pss-PT), Bombyx diapause hormone (Bom-DH), the locustamyotropins (Lom-MT) and leucopyrokinin (Lem-PK) are identical or have a high degree of homology to the C-terminus of PBANs [2].

Analytical, diagnostic and therapeutic context of Leucopyrokinin

Leucopyrokinin (LPK) analog [d-Ala(5)]-[2-8]-LPK inhibits LPK-induced analgesia in rats [3].
For studying effect of neuropeptides on digestive enzyme release, empty midgut tubes of larvae of Opisina arenosella ligated at both ends with hair were incubated with Leucokinins (LK I-VIII), LK analogues and Leucopyrokinin (LPK) in a bioassay apparatus at 37 degrees C for 30 min [4].

References

Active fragments and analogs of the insect neuropeptide leucopyrokinin: structure-function studies. Nachman, R.J., Holman, G.M., Cook, B.J. Biochem. Biophys. Res. Commun. (1986) [Pubmed]
Isolation and identification of a pheromonotropic neuropeptide from the brain-suboesophageal ganglion complex of Lymantria dispar: a new member of the PBAN family. Masler, E.P., Raina, A.K., Wagner, R.M., Kochansky, J.P. Insect Biochem. Mol. Biol. (1994) [Pubmed]
Leucopyrokinin (LPK) analog [d-Ala(5)]-[2-8]-LPK inhibits LPK-induced analgesia in rats. Plech, A., Rykaczewska-Czerwińska, M., Konopińska, D. Peptides (2004) [Pubmed]
Inhibition of digestive enzyme release by neuropeptides in larvae of Opisina arenosella (Lepidoptera: Cryptophasidae). Harshini, S., Nachman, R.J., Sreekumar, S. Comp. Biochem. Physiol. B, Biochem. Mol. Biol. (2002) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

Editor

Share