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Chemical Compound Review

KRN 8602     9-ethyl-4,6,9,10,11- pentahydroxy-7-(5...

Synonyms: LS-94099, AC1L55Y3, 131722-57-1, MX2 hydrochloride
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Disease relevance of Morpholinyl oxaunomycin


High impact information on Morpholinyl oxaunomycin


  1. KRN8602 (MX2-hydrochloride): an active new agent for the treatment of recurrent high-grade glioma. Clarke, K., Basser, R.L., Underhill, C., Mitchell, P., Bartlett, J., Cher, L., Findlay, M., Dalley, D., Pell, M., Byrne, M., Geldard, H., Hill, J.S., Maher, D., Fox, R.M., Green, M.D., Kaye, A.H. J. Clin. Oncol. (1999) [Pubmed]
  2. Phase I and pharmacokinetic study of KRN8602 alone and with filgrastim in patients with advanced cancer. Clarke, K., Basser, R.L., Maher, D., Morgan, D.J., Cebon, J., Fox, R.M., Hill, J.S., Alt, C., Bartlett, J., Geldard, H., Kaye, A.H., Green, M.D. J. Clin. Oncol. (1998) [Pubmed]
  3. Effect of filgrastim on the pharmacokinetics of MX2 hydrochloride in patients with advanced malignant disease. Morgan, D.J., Hill, J.S., Clarke, K., Stylli, S.S., Park, S.J., Cebon, J., Basser, R.L., Kaye, A.H., Geldard, H., Maher, D.W., Green, M.D. Cancer Chemother. Pharmacol. (1998) [Pubmed]
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