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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Chemical Compound Review: 

berberine    

Synonyms: Berberal, Berberin, Majarine, Thalsine, Berbinium, ...
 
 
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Disease relevance of berberine

 

Associations of berberine with other chemical compounds

  • These results suggest that the activation of AMPK is required for troglitazone-suppressed GSIS, whereas cAMP signaling pathway contributes, at least in part, to the regulatory effect of berberine on insulin secretion [2].

References

  1. Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine. Zhang, Y., Li, X., Zou, D., Liu, W., Yang, J., Zhu, N., Huo, L., Wang, M., Hong, J., Wu, P., Ren, G., Ning, G. J. Clin. Endocrinol. Metab. (2008) [Pubmed]
  2. Berberine acutely inhibits insulin secretion from beta-cells through 3',5'-cyclic adenosine 5'-monophosphate signaling pathway. Zhou, L., Wang, X., Shao, L., Yang, Y., Shang, W., Yuan, G., Jiang, B., Li, F., Tang, J., Jing, H., Chen, M. Endocrinology (2008) [Pubmed]
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