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Chemical Compound Review

AC-034     4-aminobutan-1-ol

Synonyms: AG-C-84194, AG-D-67701, ACMC-209brn, ACN-S003377, ANW-19521, ...
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High impact information on AI3-28710

  • Studies of the effects of putrescine or 4-aminobutanol on the processing of mutant AdoMetDC proenzymes are consistent with a model in which a single activator molecule interacts with buried Asp174, Glu178, and Glu256, leading to an alteration in the position of Glu11, resulting in stimulation of self-processing [1].
  • The carboxylic acid and amine precursors are based on 3-hydroxybutyrate and 4-amino-1-butanol, respectively, and have been acylated selectively using a variety of acyl donors catalyzed by porcine pancreatic lipase [2].


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