Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AC1MIVNC methyl2-[1-[(2R,3R,4S,5R)- 3,4-dihydroxy-5...

Synonyms: SureCN64345, CHEBI:20598, mcm(5)u, 5-Mcmu, 29428-50-0, ...

Lipnick, R.L. et al., Nakai, Y. et al.

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High impact information on 29428-50-0

Mass spectrometry analysis revealed an increase in 5-methoxycarbonylmethyluridine concomitant with a decrease in mcm(5)s(2)U in cy-tRNAs that were prepared from Nfs1p-depleted cells [1].
The 270-MHz proton magnetic resonance spectra of 5-carboxymethyluridine, 5-methoxycarbonylmethyluridine, and 5-carbamoylmethyluridine have been obtained, and analyzed iteratively using LAOCOON 3 [2].

References

Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs. Nakai, Y., Umeda, N., Suzuki, T., Nakai, M., Hayashi, H., Watanabe, K., Kagamiyama, H. J. Biol. Chem. (2004) [Pubmed]
A comparative proton magnetic resonance conformational study of the tRNA "wobble" nucleosides 5-carboxymethyl-, 5-methoxycarbonylmethyl-, and 5-carbamoylmethyl-uridine. Lipnick, R.L., Fissekis, J.D. Can. J. Biochem. (1980) [Pubmed]

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