Gene Review:
NFS1 - Nfs1p
Saccharomyces cerevisiae S288c
Synonyms:
Cysteine desulfurase, mitochondrial, SPL1, YCL017C, YCL17C, tRNA-splicing protein SPL1
- The Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria. Adam, A.C., Bornhövd, C., Prokisch, H., Neupert, W., Hell, K. EMBO J. (2006)
- The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins. Kispal, G., Csere, P., Prohl, C., Lill, R. EMBO J. (1999)
- The Hsp70 chaperone Ssq1p is dispensable for iron-sulfur cluster formation on the scaffold protein Isu1p. Dutkiewicz, R., Marszalek, J., Schilke, B., Craig, E.A., Lill, R., Mühlenhoff, U. J. Biol. Chem. (2006)
- Nuclear localization of yeast Nfs1p is required for cell survival. Nakai, Y., Nakai, M., Hayashi, H., Kagamiyama, H. J. Biol. Chem. (2001)
- Suppressors of superoxide dismutase (SOD1) deficiency in Saccharomyces cerevisiae. Identification of proteins predicted to mediate iron-sulfur cluster assembly. Strain, J., Lorenz, C.R., Bode, J., Garland, S., Smolen, G.A., Ta, D.T., Vickery, L.E., Culotta, V.C. J. Biol. Chem. (1998)
- SPL1-1, a Saccharomyces cerevisiae mutation affecting tRNA splicing. Kolman, C., Söll, D. J. Bacteriol. (1993)
- Characterization of iron-sulfur protein assembly in isolated mitochondria. A requirement for ATP, NADH, and reduced iron. Mühlenhoff, U., Richhardt, N., Gerber, J., Lill, R. J. Biol. Chem. (2002)
- Modifications of the lipoamide-containing mitochondrial subproteome in a yeast mutant defective in cysteine desulfurase. Onder, O., Yoon, H., Naumann, B., Hippler, M., Dancis, A., Daldal, F. Mol. Cell Proteomics (2006)
- The AUG start codon of the Saccharomyces cerevisiae NFS1 gene can be substituted for by UUG without increased initiation of translation at downstream codons. Nett, J.H., Kessl, J., Wenz, T., Trumpower, B.L. Eur. J. Biochem. (2001)
- Functional characterization of the eukaryotic cysteine desulfurase Nfs1p from Saccharomyces cerevisiae. Mühlenhoff, U., Balk, J., Richhardt, N., Kaiser, J.T., Sipos, K., Kispal, G., Lill, R. J. Biol. Chem. (2004)
- Cloning and sequence analysis of the LEU2 homologue gene from Pichia anomala. De la Rosa, J.M., Pérez, J.A., Gutiérrez, F., González, J.M., Ruiz, T., Rodríguez, L. Yeast (2001)
- Yeast mitochondrial protein, Nfs1p, coordinately regulates iron-sulfur cluster proteins, cellular iron uptake, and iron distribution. Li, J., Kogan, M., Knight, S.A., Pain, D., Dancis, A. J. Biol. Chem. (1999)
- Yeast Nfs1p is involved in thio-modification of both mitochondrial and cytoplasmic tRNAs. Nakai, Y., Umeda, N., Suzuki, T., Nakai, M., Hayashi, H., Watanabe, K., Kagamiyama, H. J. Biol. Chem. (2004)