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Chemical Compound Review

AC1MIX6Q     N-[(2R,3R,4R,5R)-4- [(2S,3R,4R,5S,6R)-3...

Synonyms: 78392-29-7, Man(6)glcnac(2), Mannosyl(6)-N-acetylglucosamine(2)
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High impact information on Man(6)glcnac(2)

  • A Man(6)GlcNAc(2) oligosaccharide attached to Asn(515) in the murine enzyme was found to extend into the active site of an adjoining protein unit in the crystal lattice in a presumed enzyme-product complex [1].

Analytical, diagnostic and therapeutic context of Man(6)glcnac(2)

  • Here, we use NMR and isothermal titration calorimetry techniques to determine carbohydrate specificity and affinities for a novel cyanobacterial protein, MVL, and show that MVL binds oligomannosides such as Man(6)GlcNAc(2) with sub-micromolar affinities [2].


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