Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Ins-P-ins bis[[(2R,3R,5S,6R)- 2,3,4,5,6...

Synonyms: SureCN4304933, AC1MJ0J0, 143491-08-1, Di-myo-inositol-1,1'-phosphate, myo-Inostil, 1,1'-(hydrogen phosphate)

Neelon, K. et al., Johnson, K.A. et al.

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High impact information on Ins-P-ins

In the sulfate-reducing archaeon Archaeoglobus fulgidus it is a metal-dependent thermozyme that catalyzes the first step in the biosynthetic pathway of the unusual osmolyte di-myo-inositol-1,1'-phosphate [1].
Inositol monophosphatase (EC 3.1.3.25) in hyperthermophilic archaea is thought to play a role in the biosynthesis of di-myo-inositol-1,1'-phosphate (DIP), an osmolyte unique to hyperthermophiles [2].

References

Probing the mechanism of the Archaeoglobus fulgidus inositol-1-phosphate synthase. Neelon, K., Wang, Y., Stec, B., Roberts, M.F. J. Biol. Chem. (2005) [Pubmed]
Crystal structure and catalytic mechanism of the MJ0109 gene product: a bifunctional enzyme with inositol monophosphatase and fructose 1,6-bisphosphatase activities. Johnson, K.A., Chen, L., Yang, H., Roberts, M.F., Stec, B. Biochemistry (2001) [Pubmed]

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