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Chemical Compound Review

PubChem14854     9-(chloromethyl)anthracene

Synonyms: CCRIS 7993, AG-E-72951, ACMC-209tez, ANW-42393, ICR 448, ...
 
 
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High impact information on ICR 448

  • The method involves 1) lipid extraction, 2) chromatographic enrichment of phospholipids with short acyl chains, 3) derivatization with 9-(chloromethyl)anthracene, 4) solid-phase extraction of the derivatives, and 5) reversed-phase HPLC with fluorescence detection [1].
  • A rapid and simple method for confirmation of the diarrhetic shellfish poisons (DSP): okadaic acid (OA), dinophysistoxin-1 (DTX-1) and dinophysistoxin-2 (DTX-2) using fluorescence detection following derivatization with 9-chloromethylanthracene, has been established as an alternate to LC/MS [2].
 

Analytical, diagnostic and therapeutic context of ICR 448

References

  1. Identification of short-chain oxidized phosphatidylcholine in human plasma. Schlame, M., Haupt, R., Wiswedel, I., Kox, W.J., Rüstow, B. J. Lipid Res. (1996) [Pubmed]
  2. Confirmation of okadaic acid, dinophysistoxin-1 and dinophysistoxin-2 in shellfish as their anthrylmethyl derivatives using UV radiation. Rawn, D.F., Ménard, C., Niedzwiadek, B., Lewis, D., Lau, B.P., Delauney-Bertoncini, N., Hennion, M.C., Lawrence, J.F. Journal of chromatography. A. (2005) [Pubmed]
  3. Liquid chromatographic determination of okadaic acid and dinophysistoxin-1 in shellfish after derivatization with 9-chloromethylanthracene. Lawrence, J.F., Roussel, S., Ménard, C. Journal of chromatography. A. (1996) [Pubmed]
 
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