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Chemical Compound Review:

Sankumin 1-[(4-chlorophenyl)-phenyl- methyl]-4...

Synonyms: Curosajin, Homodamon, Lysilan, Homorestar, Wicron, ...

Suzuki, A. et al., Yamamoto, A. et al., Nishikata, M. et al., Nishikata, M. et al., Nishikata, M. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Psychiatry related information on Homorestar

Blood sampling was performed before and during coadministration of promethazine or homochlorcyclizine and 1 week after the discontinuation, together with clinical assessments by Brief Psychiatric Rating Scale (BPRS) and Udvalg for kliniske undersogelser (UKU) side effect rating scale [1].

High impact information on Homorestar

Enantioselective pharmacokinetics of homochlorcyclizine. III. Simultaneous determination of (+)- and (-)- homochlorcyclizine in human urine by high-performance liquid chromatography [2].
Studies on drug-induced lipidosis: VII. Effects of bis-beta-diethyl-aminoethylether of hexestrol, chloroquine, homochlorocyclizine, prenylamine, and diazacholesterol on the lipid composition of rat liver and kidney [3].
The absorption of racemic homochlorcyclizine from rat small intestine was not enantioselective [4].

Analytical, diagnostic and therapeutic context of Homorestar

Enantioselective pharmacokinetics of homochlorcyclizine. II: Disposition and metabolism of (+)-, (-)- and racemic homochlorcyclizine after oral administration to man [5].

References

Histamine H1-receptor antagonists, promethazine and homochlorcyclizine, increase the steady-state plasma concentrations of haloperidol and reduced haloperidol. Suzuki, A., Yasui-Furukori, N., Mihara, K., Kondo, T., Furukori, H., Inoue, Y., Kaneko, S., Otani, K. Therapeutic drug monitoring. (2003) [Pubmed]
Enantioselective pharmacokinetics of homochlorcyclizine. III. Simultaneous determination of (+)- and (-)- homochlorcyclizine in human urine by high-performance liquid chromatography. Nishikata, M., Nakai, A., Fushida, H., Miyake, K., Arita, T., Iseki, K., Miyazaki, K., Nomura, A. J. Chromatogr. (1993) [Pubmed]
Studies on drug-induced lipidosis: VII. Effects of bis-beta-diethyl-aminoethylether of hexestrol, chloroquine, homochlorocyclizine, prenylamine, and diazacholesterol on the lipid composition of rat liver and kidney. Yamamoto, A., Adachi, S., Matsuzawa, Y., Kitani, T., Hiraoka, A., Seki, K. Lipids (1976) [Pubmed]
Enantioselective pharmacokinetics of homochlorcyclizine: disposition of (+)- and (-)-homochlorcyclizine after intravenous and oral administration of racemic homochlorcyclizine to rats. Nishikata, M., Nakai, A., Fushida, H., Miyake, K., Arita, T., Iseki, K., Miyazaki, K. J. Pharm. Pharmacol. (1994) [Pubmed]
Enantioselective pharmacokinetics of homochlorcyclizine. II: Disposition and metabolism of (+)-, (-)- and racemic homochlorcyclizine after oral administration to man. Nishikata, M., Nomura, A., Iseki, K., Miyazaki, K., Nakai, A., Fushida, H., Miyake, K., Arita, T. Eur. J. Clin. Pharmacol. (1992) [Pubmed]

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