Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

RITA [5-[5-[5- (hydroxymethyl)thiophen-2- yl]-2...

Synonyms: QC-516, cc-648, NCIChal_000017, NCIMech_000598, SureCN3437235, ...

Phillip, L.R. et al.

Phillip, Jorden, Rivera, Wolfe, Upadhyayb, Stinson,

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High impact information on NSC652287

Identification of the major metabolite of 2,5-bis(5-hydroxymethyl-2-thienyl)furan (NSC 652287), an antitumor agent, in the S9 subcellular fraction of dog liver cells [1].
A synthetic analog of 1, 2,5-bis(5-hydroxymethyl-2-thienyl)furan (2; NSC 652287) has recently been shown to possess exceptional activity and selectivity against several cell lines of the National Cancer Institute (NCI) anticancer drug screen [1].

References

Identification of the major metabolite of 2,5-bis(5-hydroxymethyl-2-thienyl)furan (NSC 652287), an antitumor agent, in the S9 subcellular fraction of dog liver cells. Phillip, L.R., Jorden, J.L., Rivera, M.I., Wolfe, T.L., Upadhyayb, K., Stinson, S.F. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (2002) [Pubmed]

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