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Chemical Compound Review: 

Mezcalin     2-(3,4,5- trimethoxyphenyl)ethanamine

Synonyms: Mescalin, Mescline, Meskalin, Mezcline, Mezcaline, ...
 
 
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Disease relevance of mescaline

  • 1 Mescaline hemi-sulphate (35 mg/kg body weight) was injected intraperitoneally into male mice (Mus musculus) from seven genetically diverse laboratory strains [1].
  • 4. Mescaline, DOM, TMA, DMA and 5 Me-ODMT also elicited myoclonus in a dose-dependent manner and in potency ratios which approximate the human experience for hallucinogenic activity [2].
 

High impact information on mescaline

  • Mescaline-induced changes of brain-cortex ribosomes. Mescaline demethylase activity of brain-cortex soluble supernatant [3].

References

  1. A comparison of the effect of mescaline on activity and emotional defaecation in seven strains of mice. Lush, I.E. Br. J. Pharmacol. (1975) [Pubmed]
  2. LSD and other related hallucinogens elicit myoclonic jumping behavior in the guinea pig. Carvey, P., Nausieda, P., Weertz, R., Klawans, H. Prog. Neuropsychopharmacol. Biol. Psychiatry (1989) [Pubmed]
  3. Mescaline-induced changes of brain-cortex ribosomes. Mescaline demethylase activity of brain-cortex soluble supernatant. Datta, R.K., Ghosh, J.J. Naunyn Schmiedebergs Arch. Pharmacol. (1977) [Pubmed]
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