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Chemical Compound Review:

Hcdd mixture 1,2,3,6,7,8- hexachlorooxanthrene

Synonyms: PCDD 67, CCRIS 323, NCI-C03703, HSDB 4154, LS-1405, ...

Iida, T. et al., Wu, C.H. et al., Holsapple, M.P. et al.

Wu, Chang-Chien, Lee,

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High impact information on CCRIS 323

Suppression of humoral antibody production by exposure to 1,2,3,6,7,8-hexachlorodibenzo-p-dioxin [1].
In 2,3,7,8-TeCDD, 1,2,3,7,8-PeCDD, 1,2,3,6,7,8-HxCDD, 1,2,3,7,8,9-HxCDD, 2,3,4,7,8-PeCDF, 1,2,3,6,7,8-HxCDF, 3,3',4,4',5-PeCB and 3,3',4,4',5,5'-HxCB concentrations, those in the breast milk of multiparas were significantly lower than those in the breast milk of primiparas (p < 0.05, lipid basis) [2].
The confirmed intermediates of 1,2,3,6,7,8-HxCDD in direct photolysis, 1,2,3,7,8-PeCDD and 2,3,7,8-TCDD both were formed by the loss of a longitudinal chlorine nearest the oxygen atom [3].

References

Suppression of humoral antibody production by exposure to 1,2,3,6,7,8-hexachlorodibenzo-p-dioxin. Holsapple, M.P., McNerney, P.J., Barnes, D.W., White, K.L. J. Pharmacol. Exp. Ther. (1984) [Pubmed]
Polychlorinated dibenzo-p-dioxins and related compounds in breast milk of Japanese primiparas and multiparas. Iida, T., Hirakawa, H., Matsueda, T., Takenaka, S., Nagayama, J. Chemosphere (1999) [Pubmed]
Photodegradation of tetra- and hexachlorodibenzo-p-dioxins. Wu, C.H., Chang-Chien, G.P., Lee, W.S. Journal of hazardous materials. (2005) [Pubmed]

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