Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

SureCN8056 [(2R,3S,4S,5R)-3,4,5- trihydroxy-5...

Synonyms: CHEMBL604196, CHEBI:16084, HMDB03971, AC1L99OC, C05345, ...

Yuen, M.H. et al., Ichihara, K. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of beta-D-Fructose 6-phosphate

In the drug-treated heart, ischemia increased the levels of G6P and F6P, but the increases were smaller than those in the saline-treated heart [1].

High impact information on beta-D-Fructose 6-phosphate

Fructose-6-phosphate,2-kinase/fructose-2,6-bisphosphatase (Fru-6-P, 2-kinase/Fru-2,6-Pase) is a bifunctional enzyme, catalyzing the interconversion of beta-D-fructose- 6-phosphate (Fru-6-P) and fructose-2,6-bisphosphate (Fru-2,6-P2) at distinct active sites [2].

References

Cardiac metabolism as an indicator of oxygen supply/demand ratio. Ichihara, K., Abiko, Y. Adv. Exp. Med. Biol. (1988) [Pubmed]
Crystal structure of the H256A mutant of rat testis fructose-6-phosphate,2-kinase/fructose-2,6-bisphosphatase. Fructose 6-phosphate in the active site leads to mechanisms for both mutant and wild type bisphosphatase activities. Yuen, M.H., Mizuguchi, H., Lee, Y.H., Cook, P.F., Uyeda, K., Hasemann, C.A. J. Biol. Chem. (1999) [Pubmed]

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