The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Grandisin     (2S,3S,4S,5S)-3,4-dimethyl- 2,5-bis(3,4,5...

Synonyms: ZINC04098808, AC1L9DK8, C10622, 53250-50-3
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on Grandisin

  • The natural products veraguensin (1) and grandisin (2) have shown potent in vitro activity against trypomastigote parasite (Y strain) with IC(50) 2.3muM (1) and 3.7muM (2) [1].
  • Six new amides, leptaglin (1), hemileptaglin (2), aglanthin (3), agleptin (4), isoagleptin (5), and leptanthin (6), together with known lignans yangambin, eudesmin, grandisin (7), epigrandisin (8), and dehydrodiconiferyl alcohol, were isolated and identified from the lipophilic leaf and stem bark extracts of Aglaia leptantha [2].


  1. Synthesis and trypanocidal activity of 1,4-bis-(3,4,5-trimethoxy-phenyl)-1,4-butanediol and 1,4-bis-(3,4-dimethoxyphenyl)-1,4-butanediol. Bernardes, L.S., Kato, M.J., Albuquerque, S., Carvalho, I. Bioorg. Med. Chem. (2006) [Pubmed]
  2. Infraspecific variation of sulfur-containing bisamides from Aglaia leptantha. Greger, H., Pacher, T., Vajrodaya, S., Bacher, M., Hofer, O. J. Nat. Prod. (2000) [Pubmed]
WikiGenes - Universities