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MeSH Review

Aglaia

 
 
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High impact information on Aglaia

  • Purified compounds of Aglaia species, namely 1H-cyclopenta[b]benzofuran lignans of the rocaglamide type as well as one aglain congener were tested for their ability to inhibit NF-kappaB activity [1].
  • Compound representatives of a new type of triterpenoid from Aglaia odorata [2].
  • Further chemical investigation of the stem bark of Aglaia cordata has led to the isolation and identification of three new lignans, namely, aglacins I-K (1-3), all of which contain two contiguous trimethoxylated phenyl systems [3].
  • Rocaglamides, glycosides, and putrescine bisamides from Aglaia dasyclada [4].
  • Four new metabolites, aglacins A-D (1-4), were identified from the methanol extract of the stem bark of Aglaia cordata [5].
 

Associations of Aglaia with chemical compounds

  • Cyclopentabenzofuran lignan protein synthesis inhibitors from Aglaia odorata [6].
  • Nine 3,4-secoapotirucallanes, argentinic acids A-I, were isolated from the bark of Aglaia argentea and transformed to their methyl esters 1-9 [7].
  • Six new amides, leptaglin (1), hemileptaglin (2), aglanthin (3), agleptin (4), isoagleptin (5), and leptanthin (6), together with known lignans yangambin, eudesmin, grandisin (7), epigrandisin (8), and dehydrodiconiferyl alcohol, were isolated and identified from the lipophilic leaf and stem bark extracts of Aglaia leptantha [8].
  • The pregnane steroid, (E)-aglawone, along with four known triterpenes, and a known sterol mixture were isolated from the bark of Aglaia lawii (Wight) Saldanha ex Ramamoorty (Meliaceae) [9].
  • Cancer chemopreventive activity of odorine and odorinol from Aglaia odorata [10].

References

  1. Rocaglamide derivatives are potent inhibitors of NF-kappa B activation in T-cells. Baumann, B., Bohnenstengel, F., Siegmund, D., Wajant, H., Weber, C., Herr, I., Debatin, K.M., Proksch, P., Wirth, T. J. Biol. Chem. (2002) [Pubmed]
  2. Compound representatives of a new type of triterpenoid from Aglaia odorata. Cai, X.H., Luo, X.D., Zhou, J., Hao, X.J. Org. Lett. (2005) [Pubmed]
  3. Aglacins I-K, three highly methoxylated lignans from Aglaia cordata. Wang, B.G., Ebel, R., Wang, C.Y., Edrada, R.A., Wray, V., Proksch, P. J. Nat. Prod. (2004) [Pubmed]
  4. Rocaglamides, glycosides, and putrescine bisamides from Aglaia dasyclada. Chaidir, n.u.l.l., Lin, W.H., Ebel, R., Edrada, R.A., Wray, V., Nimtz, M., Sumaryono, W., Proksch, P. J. Nat. Prod. (2001) [Pubmed]
  5. Aglacins A-D, first representatives of a new class of aryltetralin cyclic ether lignans from Aglaia cordata. Wang, B.G., Ebel, R., Nugroho, B.W., Prijono, D., Frank, W., Steube, K.G., Hao, X.J., Proksch, P. J. Nat. Prod. (2001) [Pubmed]
  6. Cyclopentabenzofuran lignan protein synthesis inhibitors from Aglaia odorata. Ohse, T., Ohba, S., Yamamoto, T., Koyano, T., Umezawa, K. J. Nat. Prod. (1996) [Pubmed]
  7. Cytotoxic 3,4-secoapotirucallanes from Aaglaia argentea bark. Mohamad, K., Martin, M.T., Najdar, H., Gaspard, C., Sévenet, T., Awang, K., Hadi, H., Païs, M. J. Nat. Prod. (1999) [Pubmed]
  8. Infraspecific variation of sulfur-containing bisamides from Aglaia leptantha. Greger, H., Pacher, T., Vajrodaya, S., Bacher, M., Hofer, O. J. Nat. Prod. (2000) [Pubmed]
  9. A pregnane steroid from Aglaia lawii and structure confirmation of cabraleadiol monoacetate by X-ray crystallography. Qiu, S.X., Nguyen, V.H., Le, T.X., Gu, J.Q., Lobkovsky, E., Tran, C.K., Soejarto, D.D., Clardy, J., Pezzuto, J.M., Dong, Y., Mai, V.T., Le, M.H., Fong, H.H. Phytochemistry (2001) [Pubmed]
  10. Cancer chemopreventive activity of odorine and odorinol from Aglaia odorata. Inad, A., Nishino, H., Kuchide, M., Takayasu, J., Mukainaka, T., Nobukuni, Y., Okuda, M., Tokuda, H. Biol. Pharm. Bull. (2001) [Pubmed]
 
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