Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

octylyl-CoA [(2R,3S,4R,5R)-5-(6- aminopurin-9-yl)-4...

Synonyms: octanoyl-CoA, capryloyl-CoA, n-Octanoyl-CoA, Capryloyl CoA, C8:0-CoA, ...

Wu, J. et al., Boylan, J.G. et al.

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Disease relevance of Capryloyl CoA

The k(cat) (18.8 +/- 0.5 s(-1)) and K(m) (2.5 +/- 0.4 microM) values for the oxidation of n-octanoyl-CoA (C(8)-CoA) by WT pMCAD recombinantly expressed in Escherichia coli are similar to those of native pMCAD isolated from pig kidney [1].

High impact information on Capryloyl CoA

Interactions of oleoyl- and octanoyl-coenzyme A (CoA) with phosphatidylcholine (PC) vesicles and bovine serum albumin (BSA) were investigated by NMR spectroscopy [2].

References

Probing hydrogen-bonding interactions in the active site of medium-chain acyl-CoA dehydrogenase using Raman spectroscopy. Wu, J., Bell, A.F., Luo, L., Stephens, A.W., Stankovich, M.T., Tonge, P.J. Biochemistry (2003) [Pubmed]
Interactions of acyl-coenzyme A with phosphatidylcholine bilayers and serum albumin. Boylan, J.G., Hamilton, J.A. Biochemistry (1992) [Pubmed]

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