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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Chemical Compound Review: 

GLA-63     [(2R,3R,4R,5R,6R)-4-[(3R)-3...

Synonyms: AC1L9Q7Q, 117639-49-3
 
 
 
 
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Disease relevance of GLA-63

  • Intravenous or intratumoral administration of GLA-59, GLA-60 and GLA-63 induced significant regression of Meth A fibrosarcoma in terms of tumor size, tumor weight and number of cured mice [1].

References

  1. Enhancement of nonspecific resistance to bacterial infections and tumor regressions by treatment with synthetic lipid A-subunit analogs. Critical role of N- and 3-O-linked acyl groups in 4-O-phosphono-D-glucosamine derivatives. Nakatsuka, M., Kumazawa, Y., Matsuura, M., Homma, J.Y., Kiso, M., Hasegawa, A. Int. J. Immunopharmacol. (1989) [Pubmed]
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