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Chemical Compound Review:

DECYLMALTOSIDE (2R,4S,5S)-2-[(3S,5R)-6- decoxy-4,5...

Synonyms: AC1NRATT, DECYL-BETA-D-MALTOPYRANOSIDE

Boulter, J.M. et al., Sedzik, J. et al., Hiller, R.G. et al., Philipson, K.D. et al., Purdy, M.D. et al.

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Disease relevance of DECYL-BETA-D-MALTOPYRANOSIDE

The protein was expressed in the membrane of E. coli and extracted with decylmaltoside [1].

High impact information on DECYL-BETA-D-MALTOPYRANOSIDE

The best detergents for solubilization of myelin proteins are neutral of the alkyl chain length n =9-11, as follows: dodecyl-beta-D-maltopyranoside, decyl-beta-D-maltopyranoside, n-dodecylsulfobetaine [2].
A major light-harvesting complex (LHC) has been obtained from thylakoids of Amphidinium carterae solubilized with digitonin or decylmaltoside and separated by sucrose-gradient centrifugation [3].
The nonionic detergent decylmaltoside was selected for solubilization on the basis of its efficiency to extract Glut1 from the erythrocyte membrane and its ability to maintain the protein in a monodisperse state [4].
Sarcolemma is extracted with an alkaline medium to remove peripheral proteins and is then solubilized with decylmaltoside [5].

References

Expression, purification, and initial structural characterization of YadQ, a bacterial homolog of mammalian ClC chloride channel proteins. Purdy, M.D., Wiener, M.C. FEBS Lett. (2000) [Pubmed]
Solubilization of PNS myelin membrane proteins by detergents. Sedzik, J., Tsukihara, T. Neuroreport (2000) [Pubmed]
The major intrinsic light-harvesting protein of Amphidinium: characterization and relation to other light-harvesting proteins. Hiller, R.G., Wrench, P.M., Gooley, A.P., Shoebridge, G., Breton, J. Photochem. Photobiol. (1993) [Pubmed]
Purification and characterization of human erythrocyte glucose transporter in decylmaltoside detergent solution. Boulter, J.M., Wang, D.N. Protein Expr. Purif. (2001) [Pubmed]
Purification of the cardiac Na+-Ca2+ exchange protein. Philipson, K.D., Longoni, S., Ward, R. Biochim. Biophys. Acta (1988) [Pubmed]

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