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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Chemical Compound Review: 

EP4A     N-[2-[4-[[3-butyl-5-oxo-1- [2...

Synonyms: SureCN9566072, AC1NSM2C, L-161982, A842354, L161982
 
 
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Disease relevance of L-161982

 

High impact information on L-161982

  • A selective EP4 receptor antagonist L-161982 was able to suppress IL-6 release, whereas an EP1 receptor antagonist, SC19220, was ineffective [2].

References

  1. Prostaglandin E2 promotes cell survival of glomerular epithelial cells via the EP4 receptor. Aoudjit, L., Potapov, A., Takano, T. Am. J. Physiol. Renal Physiol. (2006) [Pubmed]
  2. Up-regulation of interleukin-6 induced by prostaglandin E from invading macrophages following nerve injury: an in vivo and in vitro study. Ma, W., Quirion, R. J. Neurochem. (2005) [Pubmed]
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