Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

DEGBG 2-[[(4E)-4- (diaminomethylidenehydrazinyli d...

Synonyms: AC1NUHXB, 116173-27-4, Diethylglyoxal bis(guanylhydrazone)

Svensson, F. et al., Elo, H. et al.

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Disease relevance of AIDS-001961

Diethylglyoxal bis(guanylhydrazone), a potent inhibitor of mammalian S-adenosylmethionine decarboxylase. Effects on cell proliferation and polyamine metabolism in L1210 leukemia cells [1].

Gene context of AIDS-001961

Diethylglyoxal bis(guanylhydrazone): a novel highly potent inhibitor of S-adenosylmethionine decarboxylase with promising properties for potential chemotherapeutic use [2].

References

Diethylglyoxal bis(guanylhydrazone), a potent inhibitor of mammalian S-adenosylmethionine decarboxylase. Effects on cell proliferation and polyamine metabolism in L1210 leukemia cells. Svensson, F., Kockum, I., Persson, L. Mol. Cell. Biochem. (1993) [Pubmed]
Diethylglyoxal bis(guanylhydrazone): a novel highly potent inhibitor of S-adenosylmethionine decarboxylase with promising properties for potential chemotherapeutic use. Elo, H., Mutikainen, I., Alhonen-Hongisto, L., Laine, R., Jänne, J. Cancer Lett. (1988) [Pubmed]

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