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Chemical Compound Review

Rulide     (3R,4S,5R,6R,7R,9R,10Z,11R,12R ,13S,14R)-6...

Synonyms: Assoral, Overall, Rossitrol, Surlid, Rulid, ...
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High impact information on roxithromycin

  • We then examined the influence of RXM on inducible nitric oxide synthase (iNOS) mRNA expression in NPFs [1].
  • Addition of RXM at a dose of 7.5 microg/ml to cell cultures caused reduction of iNOS mRNA expression, which was enhanced by TNF-alpha stimulation in vitro [1].


  1. Suppressive activity of macrolide antibiotics on nitric oxide production from nasal polyp fibroblasts in vitro. Asano, K., Kamakazu, K., Hisamitsu, T., Suzaki, H. Acta Otolaryngol. (2003) [Pubmed]
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