Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Clodinafop (2R)-2-[4-(5-chloro-3-fluoro- pyridin-2...

Synonyms: SureCN21389, AC1NUN1T, DNC000450, CGA 193469, FT-0665109, ...

Roy, S. et al., Zuther, E. et al.

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High impact information on Clodinafop

Clodinafop, the most effective of the herbicides tested, inhibits growth of T. gondii in human fibroblasts by 70% at 10 microM in 2 days and effectively eliminates the parasite in 2-4 days at 10-100 microM [1].
Clodinafop-propargyl was converted to clodinafop acid by alkaline hydrolysis as clodinafop-propargyl rapidly forms bioactive clodinafop acid in soil and plant environment [2].

Analytical, diagnostic and therapeutic context of Clodinafop

The method was standardized for the determination of clodinafop residues in soil and plant samples using HPLC [2].

References

Growth of Toxoplasma gondii is inhibited by aryloxyphenoxypropionate herbicides targeting acetyl-CoA carboxylase. Zuther, E., Johnson, J.J., Haselkorn, R., McLeod, R., Gornicki, P. Proc. Natl. Acad. Sci. U.S.A. (1999) [Pubmed]
Liquid chromatographic method for the micro-quantitative determination of clodinafop in soil, wheat and Phalaris minor. Roy, S., Singh, S.B. Journal of chromatography. A. (2005) [Pubmed]

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