The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Discover     prop-2-ynyl(2R)-2-[4-(5- chloro-3-fluoro...

Synonyms: Topik, TPC-PC006, cc-170, HSDB 7007, AC-1858, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Discover

  • Molecular mechanics analysis of three crystal structures of HIV-1 protease with different inhibitors with independent calculations using the programs Discover and Brugel gave an estimate of 56-68% for the contribution of all the inhibitor main chain atoms to the total calculated protease-inhibitor interaction energy [1].

High impact information on Discover


Associations of Discover with other chemical compounds


Gene context of Discover


Analytical, diagnostic and therapeutic context of Discover


  1. Energy calculations and analysis of HIV-1 protease-inhibitor crystal structures. Gustchina, A., Sansom, C., Prevost, M., Richelle, J., Wodak, S.Y., Wlodawer, A., Weber, I.T. Protein Eng. (1994) [Pubmed]
  2. Clotrimazole, ketoconazole, and clodinafop-propargyl inhibit the in vitro growth of Babesia bigemina and Babesia bovis (Phylum Apicomplexa). Bork, S., Yokoyama, N., Matsuo, T., Claveria, F.G., Fujisaki, K., Igarashi, I. Parasitology (2003) [Pubmed]
  3. Aldose and aldehyde reductases: structure-function studies on the coenzyme and inhibitor-binding sites. El-Kabbani, O., Old, S.E., Ginell, S.L., Carper, D.A. Mol. Vis. (1999) [Pubmed]
  4. A three-layer multidatabase system for functional statistical analyses of microarray experiment results. Masseroli, M., Martucci, D., Pinciroli, F. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference (2004) [Pubmed]
  5. Helping the public 'Discover Health' in their local library. Providing health information in public libraries: a partnership approach in Scotland. Henry, E., Marley, L. Health information and libraries journal. (2004) [Pubmed]
  6. Influence of application volume on herbicide efficacy. Gauvrit, C., Lamrani-Lucotte, T., Gaudry, C. Communications in agricultural and applied biological sciences. (2003) [Pubmed]
  7. Impact of a computer-assisted education program on factors related to asthma self-management behavior. Shegog, R., Bartholomew, L.K., Parcel, G.S., Sockrider, M.M., Mâsse, L., Abramson, S.L. Journal of the American Medical Informatics Association : JAMIA. (2001) [Pubmed]
  8. Complementary modalities. Part 1. Discover the healing power of therapeutic touch. Mackey, R.B. The American journal of nursing. (1995) [Pubmed]
  9. Watch, Discover, Think, and Act: a model for patient education program development. Bartholomew, L.K., Shegog, R., Parcel, G.S., Gold, R.S., Fernandez, M., Czyzewski, D.I., Sockrider, M.M., Berlin, N. Patient education and counseling. (2000) [Pubmed]
WikiGenes - Universities