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Chemical Compound Review:

Flumicil 2-acetamido-3-sulfanyl- propanoic acid

Synonyms: L-Cysteine,, AG-G-83804, ACMC-209mvh, CCG-38902, NSC-111180, ...

Newton, G.L. et al., Steffek, M. et al.

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Disease relevance of Fluimucil

Mycothiol is comprised of N-acetylcysteine (AcCys) amide linked to 1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside (GlcN-Ins) and is the predominant thiol found in most actinomycetes [1].

High impact information on Fluimucil

Mycothiol, 1-D-myo-inosityl-2-(N-acetylcysteinyl)amido-2-deoxy-alpha-D-glucopyranoside (MSH), is composed of N-acetylcysteine (AcCys) amide linked to 1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside (GlcN-Ins) and is the major thiol produced by most actinomycetes [2].

References

Characterization of Mycobacterium tuberculosis mycothiol S-conjugate amidase. Steffek, M., Newton, G.L., Av-Gay, Y., Fahey, R.C. Biochemistry (2003) [Pubmed]
A novel mycothiol-dependent detoxification pathway in mycobacteria involving mycothiol S-conjugate amidase. Newton, G.L., Av-Gay, Y., Fahey, R.C. Biochemistry (2000) [Pubmed]

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