Chemical Compound Review:
Mucomyst (2S)-2-acetamido-3-sulfanyl- propanoic acid
Synonyms:
Airbron, Fluimucil, Fluprowit, Mucosil, Exomuc, ...
Farr,
Poon,
Dogrukol-Ak,
Drake,
Banks,
Eyerman,
Butterfield,
Morley,
Heller,
Groth,
Heller,
Breitkreutz,
Nebe,
Quintel,
Koch,
van Zandwijk,
Dalesio,
Pastorino,
de Vries,
van Tinteren,
Tepel,
van der Giet,
Schwarzfeld,
Laufer,
Liermann,
Zidek,
Kay,
Chow,
Chan,
Lo,
Kwok,
Yip,
Fan,
Lee,
Lam,
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- Opposing regulatory effects of thioredoxin and eosinophil cytotoxicity-enhancing factor on the development of human immunodeficiency virus 1. Newman, G.W., Balcewicz-Sablinska, M.K., Guarnaccia, J.R., Remold, H.G., Silberstein, D.S. J. Exp. Med. (1994)
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- The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice. Farr, S.A., Poon, H.F., Dogrukol-Ak, D., Drake, J., Banks, W.A., Eyerman, E., Butterfield, D.A., Morley, J.E. J. Neurochem. (2003)
- N-acetylcysteine reduces respiratory burst but augments neutrophil phagocytosis in intensive care unit patients. Heller, A.R., Groth, G., Heller, S.C., Breitkreutz, R., Nebe, T., Quintel, M., Koch, T. Crit. Care Med. (2001)
- Antidotal effectiveness of N-acetylcysteine in reversing acetaminophen-induced hepatotoxicity. Enhancement of the proteolysis of arylated proteins. Bruno, M.K., Cohen, S.D., Khairallah, E.A. Biochem. Pharmacol. (1988)
- A second signal recognition event required for translocation into the endoplasmic reticulum. Siegel, V. Cell (1995)
- Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Hockenbery, D.M., Oltvai, Z.N., Yin, X.M., Milliman, C.L., Korsmeyer, S.J. Cell (1993)
- Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose. Analysis of the national multicenter study (1976 to 1985). Smilkstein, M.J., Knapp, G.L., Kulig, K.W., Rumack, B.H. N. Engl. J. Med. (1988)
- In vivo induction and reversal of nitroglycerin tolerance in human coronary arteries. May, D.C., Popma, J.J., Black, W.H., Schaefer, S., Lee, H.R., Levine, B.D., Hillis, L.D. N. Engl. J. Med. (1987)
- A protein complex required for signal-sequence-specific sorting and translocation. Wiedmann, B., Sakai, H., Davis, T.A., Wiedmann, M. Nature (1994)
- Chronic ethanol ingestion impairs alveolar type II cell glutathione homeostasis and function and predisposes to endotoxin-mediated acute edematous lung injury in rats. Holguin, F., Moss, I., Brown, L.A., Guidot, D.M. J. Clin. Invest. (1998)
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- Improved outcome of paracetamol-induced fulminant hepatic failure by late administration of acetylcysteine. Harrison, P.M., Keays, R., Bray, G.P., Alexander, G.J., Williams, R. Lancet (1990)
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- Increase of ceramide and induction of mixed apoptosis/necrosis by N-(4-hydroxyphenyl)- retinamide in neuroblastoma cell lines. Maurer, B.J., Metelitsa, L.S., Seeger, R.C., Cabot, M.C., Reynolds, C.P. J. Natl. Cancer Inst. (1999)
- Modulation of transforming growth factor-beta 1 antiproliferative effects on endothelial cells by cysteine, cystine, and N-acetylcysteine. Das, S.K., White, A.C., Fanburg, B.L. J. Clin. Invest. (1992)
- Alpha-tocopherol inhibits agonist-induced monocytic cell adhesion to cultured human endothelial cells. Faruqi, R., de la Motte, C., DiCorleto, P.E. J. Clin. Invest. (1994)
- Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo. Zamzami, N., Marchetti, P., Castedo, M., Zanin, C., Vayssière, J.L., Petit, P.X., Kroemer, G. J. Exp. Med. (1995)
- Oxidative stress generated by hemorrhagic shock recruits Toll-like receptor 4 to the plasma membrane in macrophages. Powers, K.A., Szászi, K., Khadaroo, R.G., Tawadros, P.S., Marshall, J.C., Kapus, A., Rotstein, O.D. J. Exp. Med. (2006)
- mRNA expression profiles for Escherichia coli ingested by normal and phagocyte oxidase-deficient human neutrophils. Staudinger, B.J., Oberdoerster, M.A., Lewis, P.J., Rosen, H. J. Clin. Invest. (2002)
- Arabidopsis NAC1 transduces auxin signal downstream of TIR1 to promote lateral root development. Xie, Q., Frugis, G., Colgan, D., Chua, N.H. Genes Dev. (2000)
- Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse. Aoyama, K., Suh, S.W., Hamby, A.M., Liu, J., Chan, W.Y., Chen, Y., Swanson, R.A. Nat. Neurosci. (2006)
- In vivo transfer of nitric oxide between a plasma protein-bound reservoir and low molecular weight thiols. Scharfstein, J.S., Keaney, J.F., Slivka, A., Welch, G.N., Vita, J.A., Stamler, J.S., Loscalzo, J. J. Clin. Invest. (1994)
- Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. Saitoh, M., Nishitoh, H., Fujii, M., Takeda, K., Tobiume, K., Sawada, Y., Kawabata, M., Miyazono, K., Ichijo, H. EMBO J. (1998)
- SND1, a NAC Domain Transcription Factor, Is a Key Regulator of Secondary Wall Synthesis in Fibers of Arabidopsis. Zhong, R., Demura, T., Ye, Z.H. Plant Cell (2006)
- The NAC transcription factors NST1 and NST2 of Arabidopsis regulate secondary wall thickenings and are required for anther dehiscence. Mitsuda, N., Seki, M., Shinozaki, K., Ohme-Takagi, M. Plant Cell (2005)
- The yeast nascent polypeptide-associated complex initiates protein targeting to mitochondria in vivo. George, R., Beddoe, T., Landl, K., Lithgow, T. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Redox regulation of chemokine receptor expression. Saccani, A., Saccani, S., Orlando, S., Sironi, M., Bernasconi, S., Ghezzi, P., Mantovani, A., Sica, A. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Transcription switches for protoxylem and metaxylem vessel formation. Kubo, M., Udagawa, M., Nishikubo, N., Horiguchi, G., Yamaguchi, M., Ito, J., Mimura, T., Fukuda, H., Demura, T. Genes Dev. (2005)
- Acetylcysteine and speaking tracheostomy tubes. Shinnick, J.P., Freedman, A.P. JAMA (1981)
- Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes. Schmidt, A.M., Hori, O., Chen, J.X., Li, J.F., Crandall, J., Zhang, J., Cao, R., Yan, S.D., Brett, J., Stern, D. J. Clin. Invest. (1995)