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MeSH Review


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Disease relevance of Actinobacteria


High impact information on Actinobacteria


Chemical compound and disease context of Actinobacteria


Biological context of Actinobacteria


Anatomical context of Actinobacteria


Gene context of Actinobacteria

  • The parC gene was detected in actinobacteria for the first time [22].
  • (type strain VKM Ac-1804T=UCM Ac-620T) is proposed to accommodate aerobic, oxidase- and catalase-positive, weakly motile, coryneform actinobacteria isolated from leaf galls induced by the plant-parasitic nematode Heteroanguina graminophila in narrow reed grass, Calamagrostis neglecta [23].
  • Both the ClgR- and sigmaH-dependent regulation of clpC and clpP1P2 expression appears to be conserved in other actinomycetes [24].
  • The pks12 gene (Maa1979), which may be cotranscribed with a downstream gene (Maa1980), is widely conserved in the actinomycetes [25].
  • Finally, T-boxes likely involved in the regulation of translation initiation were observed upstream of ileS genes from several Actinobacteria [26].

Analytical, diagnostic and therapeutic context of Actinobacteria


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  13. GlcP constitutes the major glucose uptake system of Streptomyces coelicolor A3(2). van Wezel, G.P., Mahr, K., König, M., Traag, B.A., Pimentel-Schmitt, E.F., Willimek, A., Titgemeyer, F. Mol. Microbiol. (2005) [Pubmed]
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  15. Tropheryma whipplei Twist: a human pathogenic Actinobacteria with a reduced genome. Raoult, D., Ogata, H., Audic, S., Robert, C., Suhre, K., Drancourt, M., Claverie, J.M. Genome Res. (2003) [Pubmed]
  16. Proteomic identification of M. tuberculosis protein kinase substrates: PknB recruits GarA, a FHA domain-containing protein, through activation loop-mediated interactions. Villarino, A., Duran, R., Wehenkel, A., Fernandez, P., England, P., Brodin, P., Cole, S.T., Zimny-Arndt, U., Jungblut, P.R., Cerveñansky, C., Alzari, P.M. J. Mol. Biol. (2005) [Pubmed]
  17. A Sorangium cellulosum (myxobacterium) gene cluster for the biosynthesis of the macrolide antibiotic soraphen A: cloning, characterization, and homology to polyketide synthase genes from actinomycetes. Schupp, T., Toupet, C., Cluzel, B., Neff, S., Hill, S., Beck, J.J., Ligon, J.M. J. Bacteriol. (1995) [Pubmed]
  18. A gene encoding lysine 6-aminotransferase, which forms the beta-lactam precursor alpha-aminoadipic acid, is located in the cluster of cephamycin biosynthetic genes in Nocardia lactamdurans. Coque, J.J., Liras, P., Laiz, L., Martín, J.F. J. Bacteriol. (1991) [Pubmed]
  19. Catabolism of benzoate and phthalate in Rhodococcus sp. strain RHA1: redundancies and convergence. Patrauchan, M.A., Florizone, C., Dosanjh, M., Mohn, W.W., Davies, J., Eltis, L.D. J. Bacteriol. (2005) [Pubmed]
  20. Amphotericin B: an update. Abu-Salah, K.M. Br. J. Biomed. Sci. (1996) [Pubmed]
  21. Elastases from human and canine granulocytes, II. Interaction with protease inhibitors of animal, plant, and microbial origin. Schiessler, H., Ohlsson, K., Olsson, I., Arnhold, M., Birk, Y., Fritz, H. Hoppe-Seyler's Z. Physiol. Chem. (1977) [Pubmed]
  22. Molecular evaluation of antibiotic susceptibility: Tropheryma whipplei paradigm. Masselot, F., Boulos, A., Maurin, M., Rolain, J.M., Raoult, D. Antimicrob. Agents Chemother. (2003) [Pubmed]
  23. Agreia bicolorata gen. nov., sp. nov., to accommodate actinobacteria isolated from narrow reed grass infected by the nematode Heteroanguina graminophila. Evtushenko, L.I., Dorofeeva, L.V., Dobrovolskaya, T.G., Streshinskaya, G.M., Subbotin, S.A., Tiedje, J.M. Int. J. Syst. Evol. Microbiol. (2001) [Pubmed]
  24. clpC and clpP1P2 gene expression in Corynebacterium glutamicum is controlled by a regulatory network involving the transcriptional regulators ClgR and HspR as well as the ECF sigma factor sigmaH. Engels, S., Schweitzer, J.E., Ludwig, C., Bott, M., Schaffer, S. Mol. Microbiol. (2004) [Pubmed]
  25. Genes required for intrinsic multidrug resistance in Mycobacterium avium. Philalay, J.S., Palermo, C.O., Hauge, K.A., Rustad, T.R., Cangelosi, G.A. Antimicrob. Agents Chemother. (2004) [Pubmed]
  26. Comparative analysis of RNA regulatory elements of amino acid metabolism genes in Actinobacteria. Seliverstov, A.V., Putzer, H., Gelfand, M.S., Lyubetsky, V.A. BMC Microbiol. (2005) [Pubmed]
  27. Reverse transcriptase activity innate to DNA polymerase I and DNA topoisomerase I proteins of Streptomyces telomere complex. Bao, K., Cohen, S.N. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  28. Plasmid-borne genes code for an angular dioxygenase involved in dibenzofuran degradation by Terrabacter sp. strain YK3. Iida, T., Mukouzaka, Y., Nakamura, K., Kudo, T. Appl. Environ. Microbiol. (2002) [Pubmed]
  29. Taxonomic significance of 2,4-diaminobutyric acid isomers in the cell wall peptidoglycan of actinomycetes and reclassification of Clavibacter toxicus as Rathayibacter toxicus comb. nov. Sasaki, J., Chijimatsu, M., Suzuki, K. Int. J. Syst. Bacteriol. (1998) [Pubmed]
  30. Pelvic actinomycosis and the intrauterine contraceptive device. A cyto-histomorphologic study. Luff, R.D., Gupta, P.K., Spence, M.R., Frost, J.K. Am. J. Clin. Pathol. (1978) [Pubmed]
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