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Chemical Compound Review: 

ACMC-1C0R0     cobalt(+2) cation; dioxido-dioxo-chromium

Synonyms: AG-C-25345, AC1L1VKZ, CTK5I1583, AKOS015909378, I14-33591, ...
 
 
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Disease relevance of Cobalt chromate

  • The 163-kilobase-pair (kb) plasmid pMOL28, which determines inducible resistance to nickel, cobalt, chromate, and mercury salts in its native host Alcaligenes eutrophus CH34, was transferred to a derivative of A. eutrophus H16 and subjected to cloning procedures [1].
  • In some of the patients, concomitant sensitization to frequent contact allergens such as nickel, cobalt, chromate, or a long history of skin disease could be found; it seems reasonable to assume that in these cases the sensitization to DU was enhanced by an eczematous skin with a reduced barrier function [2].
 

High impact information on Cobalt chromate

  • METHODS: To further examine the relationship between nickel, cobalt, chromate, and the factors that may potentially be related to concurrent sensitizations to two or all three metal allergens, data from the Information Network of Dermatology Departments have been investigated [3].

References

  1. Cloning of pMOL28-encoded nickel resistance genes and expression of the genes in Alcaligenes eutrophus and Pseudomonas spp. Siddiqui, R.A., Benthin, K., Schlegel, H.G. J. Bacteriol. (1989) [Pubmed]
  2. Contact sensitivity to diazolidinyl urea (Germall II). Perret, C.M., Happle, R. Arch. Dermatol. Res. (1989) [Pubmed]
  3. A multifactorial analysis of concurrent patch-test reactions to nickel, cobalt, and chromate. Hegewald, J., Uter, W., Pfahlberg, A., Geier, J., Schnuch, A. Allergy (2005) [Pubmed]
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