Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

CCRIS 4928 1,4-dimethylphenanthrene

Synonyms: AG-E-63260, CTK4E9234, LS-102637, AKOS015904856, BRN 2439707, ...

LaVoie, E.J. et al., Sinsheimer, J.E. et al.

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Disease relevance of CCRIS 4928

Mutagenicity in Salmonella and sister chromatid exchange in mice for the bay-region syn- and anti-diol epoxides of 1,4-dimethylphenanthrene [1].

High impact information on CCRIS 4928

Among the disubstituted phenanthrenes assayed for mutagenicity, only 1,4-dimethylphenanthrene was active in the presence of metabolic activation [2].

References

Mutagenicity in Salmonella and sister chromatid exchange in mice for the bay-region syn- and anti-diol epoxides of 1,4-dimethylphenanthrene. Sinsheimer, J.E., Giri, A.K., Messerly, E.A., Jung, K.Y., Koreeda, M. Carcinogenesis (1989) [Pubmed]
Mutagenicity, tumor-initiating activity, and metabolism of methylphenanthrenes. LaVoie, E.J., Tulley-Freiler, L., Bedenko, V., Hoffman, D. Cancer Res. (1981) [Pubmed]

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