Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AC1LCVQ3 (E)-2,3-dichlorobut-2-enedioic acid

Synonyms: Dichloromaleic acid, Mucoperchloric acid, 2,3-Dichloro-2-butenedioic acid, 2-Butenedioic acid, 2,3-dichloro-

Hanna, K. et al., Christenson, W.R. et al., Christenson, W.R. et al.

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High impact information on Mucoperchloric acid

Elucidation of the PCP degradation pathway indicates that after successive PCP hydroxylations, oxidative opening of the PCP aromatic ring quickly occurred, leading to small unstable non-chlorinated or partially chlorinated short chain carboxylic acids, such as monochloroacetic and dichloromaleic acid [1].
Maleic acid (MA), a known nephrotoxicant in experimental animals, and its chlorinated derivative dichloromaleic acid (DCMA) are present in urban drinking water supplies as by-products of the chlorination process [2].
Water purification generates a variety of chlorinated contaminants, one of which is dichloromaleic acid (DCMA) [3].

References

Coupling enhanced water solubilization with cyclodextrin to indirect electrochemical treatment for pentachlorophenol contaminated soil remediation. Hanna, K., Chiron, S., Oturan, M.A. Water Res. (2005) [Pubmed]
Alterations in the renal function of male and female rats exposed to maleic acid, dichloromaleic acid, and both compounds. Christenson, W.R., Davis, M.E., Berndt, W.O. Toxicology (1989) [Pubmed]
Effect in the rat of the interaction of dichloromaleic acid and carbon tetrachloride on renal and hepatic function. Christenson, W.R., Davis, M.E., Berndt, W.O. Fundamental and applied toxicology : official journal of the Society of Toxicology. (1989) [Pubmed]

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