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Chemical Compound Review

Cgp-40215A     3-[(E)-[[N'-[(3- carbamimidoylphenyl)methyl...

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High impact information on Cgp-40215A


Analytical, diagnostic and therapeutic context of Cgp-40215A

  • Spectrophotometric titrations of CGP 40215A binding to poly(dAT)(2) have characteristics of DNA-binding-induced spectral changes as well as effects due to binding-induced protonation of the compound linker [2].


  1. In vivo trypanocidal activities of new S-adenosylmethionine decarboxylase inhibitors. Bacchi, C.J., Brun, R., Croft, S.L., Alicea, K., Bühler, Y. Antimicrob. Agents Chemother. (1996) [Pubmed]
  2. Characterization of a novel DNA minor-groove complex. Nguyen, B., Hamelberg, D., Bailly, C., Colson, P., Stanek, J., Brun, R., Neidle, S., Wilson, W.D. Biophys. J. (2004) [Pubmed]
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