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Chemical Compound Review:

CGP-45715A sodium7-[(1S,2S,3E,5Z)-10-(4- ethanoyl-3...

Synonyms:

Majumdar, T.K. et al., Capra, V. et al.

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High impact information on Cgp 45715A

Pharmacological characterization of the cysteinyl-leukotriene antagonists CGP 45715A (iralukast) and CGP 57698 in human airways in vitro [1].

Analytical, diagnostic and therapeutic context of Cgp 45715A

Iralukast (CGP 45715A) is a potent peptido-leukotriene antagonist that is active in various in vitro and animal models for the treatment of asthma [2].

References

Pharmacological characterization of the cysteinyl-leukotriene antagonists CGP 45715A (iralukast) and CGP 57698 in human airways in vitro. Capra, V., Bolla, M., Belloni, P.A., Mezzetti, M., Folco, G.C., Nicosia, S., Rovati, G.E. Br. J. Pharmacol. (1998) [Pubmed]
Trace-level quantitation of iralukast in human plasma by microbore liquid chromatography/tandem mass spectrometry. Majumdar, T.K., Bakhtiar, R., Melamed, D., Tse, F.L. Rapid Commun. Mass Spectrom. (2000) [Pubmed]

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