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Chemical Compound Review:

CCRIS 5169 (E)-4-hydroxypent-2-enal

Synonyms: AR-1G2857, LS-102037, AC1O5SS7, AC1Q6PP4, 16931-17-2, ...

Gabriel, L. et al., Tessitore, L. et al.

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Disease relevance of CCRIS 5169

Effect of two aliphatic aldehydes, methylglyoxal and 4-hydroxypentenal, on the growth of Yoshida ascites hepatoma AH-130 [1].

High impact information on CCRIS 5169

Among the aldehydes tested, 4-hydroxypentenal, produced during lipid peroxidation of biological materials, was the most active [2].

References

Effect of two aliphatic aldehydes, methylglyoxal and 4-hydroxypentenal, on the growth of Yoshida ascites hepatoma AH-130. Tessitore, L., Bonelli, G., Costelli, P., Matera, L., Pileri, A., Baccino, F.M., Dianzani, M.U. Chem. Biol. Interact. (1989) [Pubmed]
Inhibition of colchicine binding to rat liver tubulin by aldehydes and by linoleic acid hydroperoxide. Gabriel, L., Bonelli, G., Dianzani, M.U. Chem. Biol. Interact. (1977) [Pubmed]

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