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MeSH Review

Lipid Peroxidation

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Disease relevance of Lipid Peroxidation


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High impact information on Lipid Peroxidation


Chemical compound and disease context of Lipid Peroxidation


Biological context of Lipid Peroxidation


Anatomical context of Lipid Peroxidation


Associations of Lipid Peroxidation with chemical compounds


Gene context of Lipid Peroxidation


Analytical, diagnostic and therapeutic context of Lipid Peroxidation


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  2. Oxygen-dependent lipid peroxidation during lung ischemia. Fisher, A.B., Dodia, C., Tan, Z.T., Ayene, I., Eckenhoff, R.G. J. Clin. Invest. (1991) [Pubmed]
  3. Pathophysiological concentrations of glucose promote oxidative modification of low density lipoprotein by a superoxide-dependent pathway. Kawamura, M., Heinecke, J.W., Chait, A. J. Clin. Invest. (1994) [Pubmed]
  4. Aldose reductase functions as a detoxification system for lipid peroxidation products in vasculitis. Rittner, H.L., Hafner, V., Klimiuk, P.A., Szweda, L.I., Goronzy, J.J., Weyand, C.M. J. Clin. Invest. (1999) [Pubmed]
  5. In vivo externalization of phosphatidylserine and phosphatidylethanolamine in the membrane bilayer and hypercoagulability by the lipid peroxidation of erythrocytes in rats. Jain, S.K. J. Clin. Invest. (1985) [Pubmed]
  6. Elevation of 12/15 lipoxygenase products in AD and mild cognitive impairment. Yao, Y., Clark, C.M., Trojanowski, J.Q., Lee, V.M., Praticò, D. Ann. Neurol. (2005) [Pubmed]
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  12. Vitamin E suppresses isoprostane generation in vivo and reduces atherosclerosis in ApoE-deficient mice. Praticò, D., Tangirala, R.K., Rader, D.J., Rokach, J., FitzGerald, G.A. Nat. Med. (1998) [Pubmed]
  13. Role of aldose reductase and oxidative damage in diabetes and the consequent potential for therapeutic options. Srivastava, S.K., Ramana, K.V., Bhatnagar, A. Endocr. Rev. (2005) [Pubmed]
  14. Detection of endogenous malondialdehyde-deoxyguanosine adducts in human liver. Chaudhary, A.K., Nokubo, M., Reddy, G.R., Yeola, S.N., Morrow, J.D., Blair, I.A., Marnett, L.J. Science (1994) [Pubmed]
  15. Bilirubin is an antioxidant of possible physiological importance. Stocker, R., Yamamoto, Y., McDonagh, A.F., Glazer, A.N., Ames, B.N. Science (1987) [Pubmed]
  16. Cystic fibrosis, breath pentane, and lipid peroxidation. Bilton, D., Maddison, J., Webb, A.K., Seabra, L., Jones, M., Braganza, J.M. Lancet (1991) [Pubmed]
  17. Vitamin E reduces oxidant injury to mitochondria and the hepatotoxicity of taurochenodeoxycholic acid in the rat. Sokol, R.J., McKim, J.M., Goff, M.C., Ruyle, S.Z., Devereaux, M.W., Han, D., Packer, L., Everson, G. Gastroenterology (1998) [Pubmed]
  18. Increased atherosclerosis in hyperlipidemic mice deficient in alpha -tocopherol transfer protein and vitamin E. Terasawa, Y., Ladha, Z., Leonard, S.W., Morrow, J.D., Newland, D., Sanan, D., Packer, L., Traber, M.G., Farese, R.V. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  19. Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superoxide dismutase 1 mutant. Bruijn, L.I., Beal, M.F., Becher, M.W., Schulz, J.B., Wong, P.C., Price, D.L., Cleveland, D.W. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
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  21. In vitro cell injury by oxidized low density lipoprotein involves lipid hydroperoxide-induced formation of alkoxyl, lipid, and peroxyl radicals. Coffey, M.D., Cole, R.A., Colles, S.M., Chisolm, G.M. J. Clin. Invest. (1995) [Pubmed]
  22. An alcoholic binge causes massive degradation of hepatic mitochondrial DNA in mice. Mansouri, A., Gaou, I., De Kerguenec, C., Amsellem, S., Haouzi, D., Berson, A., Moreau, A., Feldmann, G., Lettéron, P., Pessayre, D., Fromenty, B. Gastroenterology (1999) [Pubmed]
  23. Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein. Okuda, M., Li, K., Beard, M.R., Showalter, L.A., Scholle, F., Lemon, S.M., Weinman, S.A. Gastroenterology (2002) [Pubmed]
  24. Impairment of macrophage functions after ingestion of Plasmodium falciparum-infected erythrocytes or isolated malarial pigment. Schwarzer, E., Turrini, F., Ulliers, D., Giribaldi, G., Ginsburg, H., Arese, P. J. Exp. Med. (1992) [Pubmed]
  25. Relationship of oxygen and glutathione in protection against carbon tetrachloride-induced hepatic microsomal lipid peroxidation and covalent binding in the rat. Rationale for the use of hyperbaric oxygen to treat carbon tetrachloride ingestion. Burk, R.F., Lane, J.M., Patel, K. J. Clin. Invest. (1984) [Pubmed]
  26. Role of daunosamine and hydroxyacetyl side chain in reaction with iron and lipid peroxidation by anthracyclines. Gianni, L., Viganò, L., Lanzi, C., Niggeler, M., Malatesta, V. J. Natl. Cancer Inst. (1988) [Pubmed]
  27. Targeted lung expression of interleukin-11 enhances murine tolerance of 100% oxygen and diminishes hyperoxia-induced DNA fragmentation. Waxman, A.B., Einarsson, O., Seres, T., Knickelbein, R.G., Warshaw, J.B., Johnston, R., Homer, R.J., Elias, J.A. J. Clin. Invest. (1998) [Pubmed]
  28. beta-Carotene: an unusual type of lipid antioxidant. Burton, G.W., Ingold, K.U. Science (1984) [Pubmed]
  29. trans-4-Hydroxy-2-hexenal: a reactive metabolite from the macrocyclic pyrrolizidine alkaloid senecionine. Segall, H.J., Wilson, D.W., Dallas, J.L., Haddon, W.F. Science (1985) [Pubmed]
  30. Prelytic damage of red cells in filtrates from peroxidizing microsomes. Roders, M.K., Glende, E.A., Recknagel, R.O. Science (1977) [Pubmed]
  31. Chlorinated methanes and liver injury: highlights of the past 50 years. Plaa, G.L. Annu. Rev. Pharmacol. Toxicol. (2000) [Pubmed]
  32. Effects of vitamin E on lipid peroxidation in healthy persons. Meagher, E.A., Barry, O.P., Lawson, J.A., Rokach, J., FitzGerald, G.A. JAMA (2001) [Pubmed]
  33. Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase. Aviram, M., Rosenblat, M., Bisgaier, C.L., Newton, R.S., Primo-Parmo, S.L., La Du, B.N. J. Clin. Invest. (1998) [Pubmed]
  34. Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null mice. Yet, S.F., Perrella, M.A., Layne, M.D., Hsieh, C.M., Maemura, K., Kobzik, L., Wiesel, P., Christou, H., Kourembanas, S., Lee, M.E. J. Clin. Invest. (1999) [Pubmed]
  35. Effects of iron loading on free radical scavenging enzymes and lipid peroxidation in rat liver. Fletcher, L.M., Roberts, F.D., Irving, M.G., Powell, L.W., Halliday, J.W. Gastroenterology (1989) [Pubmed]
  36. Enhanced cyclooxygenase-2 gene expression in alcoholic liver disease in the rat. Nanji, A.A., Miao, L., Thomas, P., Rahemtulla, A., Khwaja, S., Zhao, S., Peters, D., Tahan, S.R., Dannenberg, A.J. Gastroenterology (1997) [Pubmed]
  37. Myocardial release of malondialdehyde and purine compounds during coronary bypass surgery. Lazzarino, G., Raatikainen, P., Nuutinen, M., Nissinen, J., Tavazzi, B., Di Pierro, D., Giardina, B., Peuhkurinen, K. Circulation (1994) [Pubmed]
  38. Iron chelation by deferoxamine inhibits lipid peroxidation during cardiopulmonary bypass in humans. Menasché, P., Antebi, H., Alcindor, L.G., Teiger, E., Perez, G., Giudicelli, Y., Nordmann, R., Piwnica, A. Circulation (1990) [Pubmed]
  39. Is there a significant role for lipid peroxidation in the causation of malignancy and for antioxidants in cancer prevention? Diplock, A.T., Rice-Evans, C.A., Burdon, R.H. Cancer Res. (1994) [Pubmed]
  40. Amyloid beta-peptide impairs glucose transport in hippocampal and cortical neurons: involvement of membrane lipid peroxidation. Mark, R.J., Pang, Z., Geddes, J.W., Uchida, K., Mattson, M.P. J. Neurosci. (1997) [Pubmed]
  41. Reperfusion injury, antioxidants and hemodynamics during orthotopic liver transplantation. Goode, H.F., Webster, N.R., Howdle, P.D., Leek, J.P., Lodge, J.P., Sadek, S.A., Walker, B.E. Hepatology (1994) [Pubmed]
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