Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

CHEMBL466143 (E)-3-(4-hydroxyphenyl)-1- [2,4,6...

Synonyms: MEGxp0_001775, AC1O5YUQ, ACon1_001231, C16416, 115063-39-3, ...

Delmulle, L. et al., De Keukeleire, J. et al.

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Disease relevance of Desmethylxanthohumol

Chalcones xanthohumol (X) and desmethylxanthohumol (DMX), present in hops (Humulus lupulus L.), and the corresponding flavanones isoxanthohumol (IX, from X), 8-prenylnaringenin (8-PN, from DMX), and 6-prenylnaringenin (6-PN, from DMX), have been examined in vitro for their anti-proliferative activity on human prostate cancer cells PC-3 and DU145 [1].

High impact information on Desmethylxanthohumol

Formation and accumulation of alpha-acids, beta-acids, desmethylxanthohumol, and xanthohumol during flowering of hops (Humulus lupulus L.) [2].

References

Anti-proliferative properties of prenylated flavonoids from hops (Humulus lupulus L.) in human prostate cancer cell lines. Delmulle, L., Bellahc??ne, A., Dhooge, W., Comhaire, F., Roelens, F., Huvaere, K., Heyerick, A., Castronovo, V., De Keukeleire, D. Phytomedicine (2006) [Pubmed]
Formation and accumulation of alpha-acids, beta-acids, desmethylxanthohumol, and xanthohumol during flowering of hops (Humulus lupulus L.). De Keukeleire, J., Ooms, G., Heyerick, A., Roldan-Ruiz, I., Van Bockstaele, E., De Keukeleire, D. J. Agric. Food Chem. (2003) [Pubmed]

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