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Chemical Compound Review

Mdl 28753     4-[(Z,1S)-1-(2- carboxyethylsulfanyl)-11...

Synonyms: Mdl 28,753, AC1O512V, 129509-46-2
 
 
 
 
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High impact information on Mdl 28753

  • In the isolated longitudinal muscle of the guinea pig ileum, MDL 28,753 was a full agonist at the leukotriene (LT) D4 receptor and had a pD2 of 8.9 compared with a pD2 of 9.2 for LTD4 [1].

References

  1. MDL 28,753, an agonist of LTD4 but an antagonist of LTC4 in longitudinal muscle of guinea pig ileum. Gieske, T.H., Sabol, J.S., Raddatz, R. J. Pharmacol. Exp. Ther. (1990) [Pubmed]
 
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